Causes and Symtoms.

It is believed that H. pylori's shape and characteristics cause the damage that leads to ulcers.

Because of their shape and the way they move, the bacteria can penetrate the stomach's protective mucous lining where they produce the enzyme urease, which generates substances that neutralize the stomach's acids. This weakens the stomach's protective mucus, makes the stomach cells more susceptible to the damaging effects of acid and pepsin, and leads to sores or ulcers in the stomach or duodenum.

The bacteria can also attach to stomach cells, further weakening the stomach's defensive mechanisms and producing local inflammation. For reasons not completely understood, H. pylori can also stimulate the stomach to produce more acid.

What are the symptoms of H. pylori-related ulcers?
The following are the most common symptoms for ulcers, however, each individual may experience symptoms differently.

Soon after being infected with H. pylori, most people develop gastritis -- an inflammation of the stomach lining. However, most people will never have symptoms or problems related to the infection. When symptoms are present, they may include:

• dull, gnawing pain, which may:
  • occur 2-3 hours after a meal
  • come and go for several days or weeks
  • occur in the middle of the night when stomach is empty
  • be relieved by eating
• loss of weight
• loss of appetite
• bloating
• burping
• nausea
• vomiting

The symptoms of ulcers may resemble other conditions or medical problems. Consult your physician for a diagnosis.

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